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Related Experiment Videos

Case report: osteolytic osteosarcoma in a German Shepherd bitch.

A Bundza, A S Greig, G W Speckmann

    The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
    |February 1, 1979
    PubMed
    Summary

    A German Shepherd developed a malignant osteosarcoma in its rib, spreading to the lungs and spleen. This aggressive bone cancer required detailed examination, including electron microscopy, for diagnosis.

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    Area of Science:

    • Veterinary Pathology
    • Canine Oncology

    Background:

    • Osteosarcoma is a common primary bone tumor in dogs, often affecting long bones but can arise from other skeletal sites.
    • Early detection and accurate diagnosis are crucial for managing canine osteosarcoma and determining prognosis.

    Observation:

    • A six-year-old German Shepherd presented with a large thoracic mass originating from the right fourth rib.
    • Gross examination revealed an oval mass with significant rib involvement.

    Findings:

    • Cytological and histopathological analysis confirmed an osteolytic osteosarcoma.
    • The tumor exhibited extreme cellular pleomorphism, including giant cells and atypical mitoses, with abundant osteoblastic stroma.
    • Metastases were identified in the lung and spleen.
    • Electron microscopy supported the diagnosis of osteosarcoma.

    Implications:

    • This case highlights the potential for osteosarcoma to arise from atypical locations like ribs in large breed dogs.
    • The aggressive nature and metastatic potential underscore the importance of thorough diagnostic workups for suspected bone tumors.
    • Understanding the histopathological features aids in accurate grading and treatment planning for canine osteosarcoma.

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