Related Experiment Video
Updated: Mar 1, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Fetal Cardiac US: Techniques and Normal Anatomy Correlated with Adult CT and MR Imaging
Neel Patel1, Evan Narasimhan1, Anne Kennedy1
1From the Department of Radiology and Imaging Sciences, University of Utah Hospital and Clinics, 30 N 1099 E, Room 1A71, Salt Lake City, Utah 84132.
Insights
Improving prenatal screening for congenital heart disease (CHD) is crucial. This study offers a checklist and stepwise approach for community radiologists to enhance fetal cardiac anatomy assessment via ultrasonography (US), improving early detection rates.
Area of Science:
- Medical Imaging
- Radiology
- Pediatric Cardiology
Background:
- Congenital heart disease (CHD) is a leading cause of childhood mortality.
- Current prenatal ultrasonography (US) screening for CHD has suboptimal detection rates.
- Enhancing initial screenings in low-risk populations offers the greatest population health impact.
Purpose of the Study:
- To present a stepwise process for evaluating fetal cardiac anatomy.
- To provide a checklist for assessing the four-chamber view and outflow tracts.
- To improve prenatal detection rates of CHD through standardized US screening.
Main Methods:
- Developed a stepwise protocol for fetal cardiac US evaluation.
- Utilized comparisons with CT and MR imaging for anatomical reference.
- Included specific views: four-chamber, outflow tracts, aortic arch, bicaval, three-vessel view (3VV), and three-vessel trachea view (3TV).
Main Results:
- Presents a structured approach to fetal cardiac US screening.
- Demonstrates normal appearances of key cardiac views.
- Offers a checklist to aid community radiologists in identifying potential abnormalities.
Conclusions:
- A standardized checklist and stepwise evaluation improve fetal cardiac US screening.
- Early and accurate diagnosis of CHD enables timely intervention and personalized management.
- Improved screening can reduce mortality and morbidity associated with undiagnosed CHD.
Abstract:
Congenital heart disease (CHD) is an important cause of childhood mortality. Despite the widespread use of ultrasonography (US) as a screening tool, the prenatal detection rate is suboptimal. Improvement of the initial screening examination, which is performed in low-risk populations and often interpreted by community radiologists, targets a point in the screening process that is likely to have the largest population effect. If the goal of community-based screenings is to detect cases that may be abnormal and refer those to specialized centers for complete assessment, it is logical to use a checklist to confirm normal anatomy. This article presents a stepwise process to evaluate fetal cardiac anatomy using comparison with computed tomography (CT) and magnetic resonance (MR) images, which are more familiar to radiologists in busy general practices. In addition, this article presents a checklist for assessment of the four-chamber view and demonstrates the expected normal appearance of the outflow tract views as well as the additional views required for complex obstetric US. These additional views include the aortic arch and bicaval views, three-vessel view (3VV), and three-vessel trachea view (3TV). CHD may be isolated, but it may indicate aneuploidy or a syndrome that, if present, determines the prognosis. In isolated CHD, the prognosis is determined by the exact nature of the abnormalities. In particular, duct-dependent disease if undiagnosed results in circulatory collapse in the infant once the ductus closes. If the heart does not look normal, the patient should be referred for detailed evaluation. Timely diagnosis of significant CHD allows for development of a personalized pregnancy management plan. © RSNA, 2017.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System IV: CMRI

