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karyoploteR: an R/Bioconductor package to plot customizable genomes displaying arbitrary data.

Bernat Gel1, Eduard Serra1,2

  • 1Hereditary Cancer Group, Program for Predictive and Personalized Medicine of Cancer - Germans Trias i Pujol Research Institute (PMPPC-IGTP), Campus Can Ruti, Badalona, Spain.

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Summary

karyoploteR is a new R/Bioconductor package for creating customizable linear genome plots. It enables flexible visualization of genomic data and annotations for any species.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Data Visualization

Background:

  • Data visualization is essential for exploring and interpreting genomic data.
  • Existing tools lack customizable non-circular whole-genome plotting capabilities for diverse species.

Purpose of the Study:

  • To develop a flexible R/Bioconductor package for creating customizable linear genome plots.
  • To enable visualization of genomic annotations and experimental data along chromosomal representations.

Main Methods:

  • Developed karyoploteR, an R/Bioconductor package.
  • Utilized R base graphics principles for plot creation.
  • Implemented a main function for base karyoplots and additional functions for data integration and customization.

Main Results:

  • karyoploteR allows creation of linear chromosomal representations for any genome.
  • The package supports plotting genomic annotations and experimental data.
  • Highly customizable plots can be generated with freedom in data positioning and representation.

Conclusions:

  • karyoploteR provides a versatile solution for non-circular whole-genome visualization.
  • The package enhances the exploration and interpretation of genomic data across species.