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Updated: Mar 1, 2026
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Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells
Published on: April 16, 2012
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Curbing Tregs' (Lack of) Enthusiasm
Taha Merghoub1, Jedd D Wolchok2
1Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Ludwig Institute for Cancer Research, New York, NY 10065, USA; Parker Institute for Cancer Immunotherapy, New York, NY 10065, USA.
Cell
|June 3, 2017
Abstract:
In this issue, Overacre-Delgoffe et al. show that interferon gamma production by a subset of regulatory T cells in the tumor microenvironment triggers Treg instability locally and restores anti-tumor immunity.
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