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Updated: Mar 1, 2026

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
Published on: November 21, 2023
Sensorimotor experience and verb-category mapping in human sensory, motor and parietal neurons
Ying Yang1, Michael Walsh Dickey2, Julie Fiez3
1Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA; School of Electronics, Electrical Engineering and Computer Science, Queen's University, Belfast, United Kingdom.
Abstract:
Semantic grounding is the process of relating meaning to symbols (e.g., words). It is the foundation for creating a representational symbolic system such as language. Semantic grounding for verb meaning is hypothesized to be achieved through two mechanisms: sensorimotor mapping, i.e., directly encoding the sensorimotor experiences the verb describes, and verb-category mapping, i.e., encoding the abstract category a verb belongs to. These two mechanisms were investigated by examining neuronal-level spike (i.e. neuronal action potential) activities from the motor, somatosensory and parietal areas in two human participants. Motor and a portion of somatosensory neurons were found to be involved in primarily sensorimotor mapping, while parietal and some somatosensory neurons were found to be involved in both sensorimotor and verb-category mapping. The time course of the spike activities and the selective tuning pattern of these neurons indicate that they belong to a large neural network used for semantic processing. This study is the first step towards understanding how words are processed by neurons.
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