Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Motor Unit Stimulation01:20

Motor Unit Stimulation

4.1K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
4.1K
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

4.9K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Handling the challenges of accessing reliable and tailored information on physical activity during pregnancy: a mixed-methods, cross-perspective investigation.

BMC pregnancy and childbirth·2026
Same author

Accuracy and homogeneity of dictionary-based T2-mapping dedicated to single slice and multi-slice multi-echo turbo-spin echo imaging.

Magnetic resonance imaging·2026
Same author

Decoding hypnotic consciousness: neural and experiential insights into induced and ideomotor suggestions.

Neuroscience of consciousness·2026
Same author

Functional Segregation of Epileptogenicity within the Human Amygdala.

Annals of neurology·2026
Same author

Gastric Volumetric Filling Capacity Before and After Sleeve Gastrectomy: a Magnetic Resonance Imaging and Biomechanical Study.

Obesity surgery·2026
Same author

DyABD: the abdominal muscle segmentation in dynamic MRI benchmark.

BMC medical imaging·2026

Related Experiment Video

Updated: Mar 1, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

22.9K

Specific brain activation patterns associated with two neuromuscular electrical stimulation protocols.

Jennifer Wegrzyk1, Jean-Philippe Ranjeva1, Alexandre Fouré1

  • 1Aix Marseille Univ, CNRS, CRMBM, UMR 7339, 13385, Marseille, France.

Scientific Reports
|June 4, 2017
PubMed
Summary
This summary is machine-generated.

Neuromuscular electrical stimulation (NMES) parameters influence brain activation. Different NMES protocols, varying in sensory input, target distinct brain regions, potentially enabling personalized rehabilitation for patients unable to perform voluntary movements.

More Related Videos

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
07:47

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function

Published on: February 4, 2016

13.7K
Assessing Primary Motor Cortex Excitability and Excitability Modulation by Pairing Transcranial Magnetic Stimulation with Electromyography
12:13

Assessing Primary Motor Cortex Excitability and Excitability Modulation by Pairing Transcranial Magnetic Stimulation with Electromyography

Published on: October 7, 2025

776

Related Experiment Videos

Last Updated: Mar 1, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

22.9K
Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
07:47

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function

Published on: February 4, 2016

13.7K
Assessing Primary Motor Cortex Excitability and Excitability Modulation by Pairing Transcranial Magnetic Stimulation with Electromyography
12:13

Assessing Primary Motor Cortex Excitability and Excitability Modulation by Pairing Transcranial Magnetic Stimulation with Electromyography

Published on: October 7, 2025

776

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Neuromuscular electrical stimulation (NMES) is used in rehabilitation.
  • The impact of NMES parameters on brain activity is not well understood.
  • Understanding brain activation patterns is crucial for optimizing NMES protocols.

Purpose of the Study:

  • To compare brain activation patterns between two NMES protocols with different sensory inputs.
  • To investigate the relationship between NMES parameters and cerebral activation.
  • To explore the potential for tailored NMES rehabilitation strategies.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) in 16 healthy subjects.
  • Comparison of wide-pulse high-frequency (WPHF) and conventional (CONV) NMES protocols on triceps surae.
  • Isometric contractions at 10% maximal force, with voluntary contractions (VOL) as control.

Main Results:

  • Both WPHF and CONV NMES activated sensorimotor network, cerebellum, and thalamus.
  • WPHF NMES showed less deactivation in somatosensory cortex and precuneus compared to CONV.
  • CONV NMES led to hyperactivation in bilateral thalami and caudate nuclei.
  • Brain activation differences correlated with total current charge, not mean force.

Conclusions:

  • NMES parameter modulation influences specific brain region activation and deactivation.
  • WPHF and CONV NMES protocols differentially engage cerebral networks.
  • These findings suggest potential for personalized NMES rehabilitation in patients with limited voluntary movement.