Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regression Toward the Mean01:52

Regression Toward the Mean

7.2K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
7.2K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Teratogenicity01:07

Teratogenicity

4.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.4K
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

72.3K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
72.3K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.8K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.8K
Probability Laws01:49

Probability Laws

44.7K
Overview
44.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caregiving Across Distances: Residential Proximity, Care Activities, and Mental Health.

The Gerontologist·2026
Same author

Bleeding-related quality of life in older adults: Psychometric evaluation of the HEmorrhage Life Impact indeX (HELIX).

Thrombosis research·2026
Same author

The association of sociodemographic differences with clinical management following a diagnosis of short cervix.

Pregnancy (Hoboken, N.J.)·2026
Same author

Experiences of pregnant and postpartum people of color engaged in a randomized clinical trial of medication to treat opioid use disorder during pregnancy: A "Positive Outliers" analysis.

Journal of substance use and addiction treatment·2026
Same author

Evaluation of Family History of Diabetes and the Development of Cystic Fibrosis-Related Diabetes in a Clinical Cystic Fibrosis Cohort.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same author

Treatment of Haemophilia A Without Inhibitors: Real-World Treatment Patterns and Clinical Outcomes in the US.

Haemophilia : the official journal of the World Federation of Hemophilia·2026
Same journal

Double versus single emergency cervical cerclage combined with vaginal progesterone: a multicenter, non-blinded, randomized controlled trial.

American journal of obstetrics and gynecology·2026
Same journal

Fibroblast heterogeneity and abnormal phenotype transition in vaginal wall prolapse at single-nucleus transcriptional resolution.

American journal of obstetrics and gynecology·2026
Same journal

Early patient removal of urinary catheters after urogynecologic surgery, a randomized trial.

American journal of obstetrics and gynecology·2026
Same journal

Standard vs. Lower Pressure Pneumoperitoneum in Laparoscopic Gynecologic Surgery: A Randomized Controlled Trial.

American journal of obstetrics and gynecology·2026
Same journal

Association of Surgical Approach with Oncologic Outcomes in Low-Risk Cervical Cancer.

American journal of obstetrics and gynecology·2026
Same journal

Trends in Infertility Treatments by Race, Ethnicity, Socioeconomic Status, and Region in U.S. Birth Certificates from Live Births: 2011-2022.

American journal of obstetrics and gynecology·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.6K

Maternal race and intergenerational preterm birth recurrence.

Marcela C Smid1, Jong Hyung Lee2, Jacqueline H Grant3

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina-Chapel Hill, Chapel Hill, NC; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT.

American Journal of Obstetrics and Gynecology
|June 5, 2017
PubMed
Summary
This summary is machine-generated.

Black mothers born preterm have an increased risk of delivering preterm themselves, unlike White mothers. Early preterm birth in Black mothers born before 34 weeks poses the highest risk for delivering very preterm.

Keywords:
health disparityintergenerational recurrenceperinatal epidemiologypreterm birthracial disparity

More Related Videos

A Preterm Rat Model for Pain Studies
01:37

A Preterm Rat Model for Pain Studies

Published on: February 9, 2024

840
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
04:18

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

607

Related Experiment Videos

Last Updated: Mar 1, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.6K
A Preterm Rat Model for Pain Studies
01:37

A Preterm Rat Model for Pain Studies

Published on: February 9, 2024

840
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
04:18

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

607

Area of Science:

  • Reproductive Health
  • Genetics and Genomics
  • Perinatal Epidemiology

Background:

  • Preterm birth is a complex condition with a genetic component, with studies showing increased risk in White women born preterm.
  • The intergenerational risk of preterm birth is not well-defined for Black women.
  • This study addresses the gap in understanding preterm birth recurrence across generations in Black women.

Purpose of the Study:

  • To evaluate and compare the intergenerational risk of preterm birth between non-Hispanic Black and non-Hispanic White mothers.
  • To identify specific risk factors and disparities in preterm birth recurrence based on maternal race and gestational age at birth.

Main Methods:

  • Population-based retrospective cohort study using the Virginia Intergenerational Linked Birth File.
  • Included non-Hispanic Black and White mothers born 1960-1996, delivering their first singleton infant between 2005-2009.
  • Used Cox regression, Kaplan-Meier functions, and multivariable logistic regression to analyze preterm birth risk, adjusting for confounders.

Main Results:

  • Non-Hispanic Black mothers were more likely to have been born preterm (late or early) compared to non-Hispanic White mothers.
  • Non-Hispanic White mothers born preterm did not show an increased risk of subsequent preterm delivery.
  • Black mothers born early preterm (<34 weeks) had the highest adjusted odds ratio (3.26) for delivering their first child preterm.

Conclusions:

  • An intergenerational effect of preterm birth was observed in non-Hispanic Black mothers, but not in non-Hispanic White mothers.
  • Black mothers born before 34 weeks gestation face the highest risk of delivering their first child very preterm.
  • Further research is needed to understand the pathways contributing to this racial disparity in intergenerational preterm birth.