Related Experiment Video
Updated: Mar 1, 2026

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
Published on: July 3, 2018
Surface properties and surface free energy of cellulosic etc mucoadhesive polymers
M Rojewska1, A Bartkowiak1, B Strzemiecka1
1Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo Str., 60-965, Poznan, Poland.
Abstract:
The paper presents the sorption and wettability properties for several mucoadhesive polymers (Carbopol 974P NF (carbomer polymer; carboxy polymethylene), Noveon AA-1, (polycarbophil; acrylic acid polymer crosslinked with divinyl glycol) HPMC (hypromellose; cellulose 2-hydroxyethyl methyl ester) and HEC (cellulose 2-hydroxyethyl ether) and a film-forming polymer Kollidon VA 64 (polyvinylpyrrolidone-vinyl acetate copolymer)) commonly used in controlled drug delivery systems. Moreover, the surface energy of powders was determined using the data obtained according to the three types of experimental investigation. The contact angle measurements for powders were performed according to the Washburn method and using the capillary rise technique. Whereas the sessile drop method was performed on the compressed discs of mucoadhesive polymers. For the surface characterization the IGC technique was also applied. The results obtained by different methods, for both: wettability and surface energies, were compared and correlated. The presented study showed significant differences in the morphology and surface properties of mucoadhesion polymers considered. It was confirmed that for the accurate quantification of the free surface energy (and its components), for mucoadhesive polymers considered, not only the IGC in finite concentration, but also the Washburn method should be used.
Related Concept Videos
Adhesion
Capillary action is a result of water’s adhesive tendencies. When a narrow...
Surface Tension, Capillary Action, and Viscosity
The various IMFs between identical molecules of a substance are examples of cohesive forces. The molecules within a liquid are surrounded by other molecules and are attracted equally in all directions by the cohesive forces within the liquid. However, the molecules on the surface of a liquid are attracted only by about one-half as many molecules. Because of the unbalanced molecular attractions on the surface molecules, liquids contract to form a shape that minimizes the number...
Cell Adhesion Molecules - Types and Functions
CAM Families
The Integrin family of proteins is primarily involved...
Cell Adhesion in Plants
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
Surface Active Agents
Micelles

