Related Experiment Video
Updated: Mar 1, 2026
CD Spectroscopy to Study DNA-Protein Interactions
Published on: February 10, 2022
DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest
Lee Whitmore1, Lazaros Mavridis2, B A Wallace1
1Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.
Abstract:
Circular dichroism spectroscopy is a well-used, but simple method in structural biology for providing information on the secondary structure and folds of proteins. DichroMatch (DM@PCDDB) is an online tool that is newly available in the Protein Circular Dichroism Data Bank (PCDDB), which takes advantage of the wealth of spectral and metadata deposited therein, to enable identification of spectral nearest neighbors of a query protein based on four different methods of spectral matching. DM@PCDDB can potentially provide novel information about structural relationships between proteins and can be used in comparison studies of protein homologs and orthologs.
