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Static beam tomotherapy as an optimisation method in whole-breast radiation therapy (WBRT)
Matthew Squires1, Yunfei Hu2, Mikel Byrne3
1Precision Cancer Care, Australia.
Journal of Medical Radiation Sciences
|June 6, 2017
Summary
TomoDirect™ (TD) offers a suitable whole-breast radiation therapy (WBRT) approach, demonstrating comparable plan quality to intensity modulated radiation therapy (IMRT) while significantly reducing planning time.
Area of Science:
- Radiation Oncology
- Medical Physics
Background:
- TomoTherapy introduced TomoDirect™ (TD), a static form of tomotherapy.
- This study evaluates TD against intensity modulated radiation therapy (IMRT) for breast cancer treatment.
Purpose of the Study:
- Compare target and organ at risk (OAR) doses of TD and IMRT for whole-breast radiation therapy (WBRT).
- Assess the planning efficiency of TD by measuring optimization times.
Main Methods:
- 27 whole-breast radiation therapy (WBRT) patient plans treated with IMRT were replanned using TomoDirect™ (TD).
- Prescribed dose: 50 Gy in 25 fractions. Planning time was recorded.
- Analysis focused on ICRU-based planning metrics, including PTV D99 for comparison.
Main Results:
- Both TD and IMRT met ICRU50 target heterogeneity objectives.
- TD plans showed a statistically significant reduction in ipsilateral lung V5 doses.
- TD significantly reduced planning time by an average of 17.8 minutes per patient compared to IMRT.
Conclusions:
- TomoDirect™ (TD) is a suitable treatment approach for whole-breast radiation therapy (WBRT).
- TD offers comparable plan quality to IMRT while improving planning efficiency.
