Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Advances in clinical toxicology.

M T Boehnert, W J Lewander, P Gaudreault

    Pediatric Clinics of North America
    |February 1, 1985
    PubMed
    Summary

    This review covers acute overdose management, focusing on gastrointestinal decontamination methods like activated charcoal and systemic antidotes such as pyridoxine and naloxone. It highlights special cases including disc battery and cocaine packet ingestion.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode.

    Archives of disease in childhood·2003
    Same author

    Hepatitis C prevalence and risk behavior of injecting drug users in Sydney: a continuing concern.

    The Southeast Asian journal of tropical medicine and public health·2002
    Same author

    Prevalence of potential risk factors in victims of electrocution.

    Forensic science international·2001
    Same author

    Clinical toxicology: built better than they knew. Reflections on yesterday, today and tomorrow.

    Veterinary and human toxicology·2001
    Same author

    Drug use and social circumstances: a study among different target groups in northwest Bangladesh.

    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence·2001
    Same author

    Will current training programs prepare pediatricians to meet the health care needs of children in the 21st century? An opinion.

    The Journal of pediatrics·2001

    Area of Science:

    • Toxicology
    • Emergency Medicine

    Background:

    • Acute overdose management requires effective strategies for both removing ingested toxins and administering specific antidotes.
    • Understanding the mechanisms and efficacy of various decontamination techniques is crucial for patient outcomes.

    Purpose of the Study:

    • To review current data on gastrointestinal decontamination and systemic antidotes for acute overdose.
    • To discuss the effectiveness of various methods and highlight special ingestion scenarios.

    Main Methods:

    • Literature review of gastrointestinal decontamination techniques (Ipecac syrup, gastric lavage, activated charcoal, etc.).
    • Review of systemic antidotes, including pyridoxine and naloxone.
    • Analysis of specific challenges in acute overdose management.

    Main Results:

    • Various gastrointestinal decontamination methods have different mechanisms and effectiveness profiles.
    • Activated charcoal, gastric lavage, and saline cathartics are discussed for toxin removal.
    • Pyridoxine and naloxone are detailed as key systemic antidotes.

    Conclusions:

    • Effective management of acute overdose involves a combination of appropriate gastrointestinal decontamination and timely administration of specific antidotes.
    • Special considerations are necessary for unique ingestions, such as disc batteries and illicit substance packets.

    Related Experiment Videos