Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

61.0K
Overview
61.0K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

371
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
371
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

233
Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
233
Hand hygiene01:23

Hand hygiene

6.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
6.3K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

7.1K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
7.1K
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

1.6K
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of (+)-erythro-mefloquine as an active enantiomer with greater efficacy than mefloquine against Mycobacterium avium infection in mice.

Antimicrobial agents and chemotherapy·2012
Same author

Reconsidering some approved antimicrobial agents for tuberculosis.

Antimicrobial agents and chemotherapy·2009
Same author

EDP-420, a bicyclolide (bridged bicyclic macrolide), is active against Mycobacterium avium.

Antimicrobial agents and chemotherapy·2007
Same author

In vivo efficacy of phage therapy for Mycobacterium avium infection as delivered by a nonvirulent mycobacterium.

Microbial drug resistance (Larchmont, N.Y.)·2006
Same author

Genomic approach to identifying the putative target of and mechanisms of resistance to mefloquine in mycobacteria.

Antimicrobial agents and chemotherapy·2005
Same author

Destroying the life and career of a valued physician-scientist who tried to protect us from plague: was it really necessary?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2005

Related Experiment Video

Updated: Mar 1, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.4K

Antibiotic Update for the Surgeon.

Lowell S Young1

  • 1Director, Kuzell Institute for Arthritis and Infectious Diseases; Chief, Division of Infectious Disease, California Pacific Medical Center; Clinical Professor of Medicine, UCSF, San Francisco, California.

Surgical Technology International
|June 6, 2017
PubMed
Summary
This summary is machine-generated.

The pharmaceutical industry is developing new drugs with increased potency and broader applications. Even incremental advancements in safety, toxicity, cost, or convenience can significantly benefit patient care.

More Related Videos

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K

Related Experiment Videos

Last Updated: Mar 1, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.4K
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K

Area of Science:

  • Pharmaceutical Science
  • Drug Development
  • Clinical Pharmacology

Background:

  • The pipeline for new antimicrobial agents is expanding.
  • This trend of increasing drug development is also evident in anti-inflammatory and cardiovascular fields.
  • Not all new drugs are groundbreaking; some are considered 'me too' drugs.

Purpose of the Study:

  • To analyze the landscape of new drug introductions in clinical practice.
  • To evaluate the significance of incremental improvements in drug therapy.
  • To highlight the value of new agents that offer advantages in safety, cost, or usability.

Main Methods:

  • Review of current pharmaceutical industry trends.
  • Analysis of drug development across various therapeutic areas.
  • Assessment of criteria for evaluating new therapeutic agents.

Main Results:

  • A continuous increase in the number of new antimicrobial agents is observed.
  • New compounds with enhanced potency and broader therapeutic applicability are consistently introduced across multiple fields.
  • Incremental improvements in drug properties (safety, cost, convenience) are valuable.

Conclusions:

  • The pharmaceutical industry is actively developing a growing number of new drugs.
  • New drug entities, even those not representing major breakthroughs, can offer significant clinical value.
  • Improvements in safety, toxicity, cost-effectiveness, and ease of use are critical factors for the adoption of new therapies.