Related Experiment Video
Updated: Mar 1, 2026

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
A Technique of Carotid Endarterectomy and Carotid Shunting
Toshio Inahara1, John C Mayberry1, Dipankar Mukherjee1
1Department of Surgery, St Vincent Hospital and Medical Center, Portland, Oregon.
Abstract:
With the advent of carotid arterial operations, concerns of interruption of cerebral perfusion and ischemic injury loomed as the major deterrent. The physiologic basis for cerebral protection is to diminish its oxygen requirement by chemical or hypothermic means or to continue its adequate arterial perfusion. The first successful carotid reconstruction resecting an internal carotid stenosis with anastomosis of the patent external carotid to the distal internal carotid artery was performed by Carrea of Argentina in 1951. Preoperatively, ascorbic acid and phenobarbital was given but its rationale was not explained.

