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Updated: Mar 1, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Advances in Automated Assessment of Intracoronary Optical Coherence Tomography and Their Clinical Application
Giovanni J Ughi1, Tom Adriaenssens2
1Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium; Department of Cardiovascular Diseases, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
Abstract:
Intravascular optical coherence tomography (OCT) is capable of acquiring 3-dimensional (3D) data of coronary arteries allowing for the assessment of plaques, stents, thrombus, side branches, and other relevant structures in a 3D fashion. Given that state-of-the-art OCT systems acquire images at a very high frame rate (up to 200 frames per second), typically a very large number of images per pullback (ie, 500 or more) need to be analyzed. The manual assessment of stents, plaques, and other structures is time-consuming, cumbersome, and inefficient and thus not suitable for on-line analysis during percutaneous coronary intervention procedures.
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