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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
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Optimal Antiplatelet Therapy in ST-Segment Elevation Myocardial Infarction

Rafael Harari1, Usman Baber1

  • 1Department of Cardiology, The Mount Sinai Hospital, One Gustave L. Levy Place, New York, NY 10029-6574, USA.

Interventional Cardiology Clinics
|June 6, 2017
PubMed

Insights

Antiplatelet therapy is crucial for treating myocardial infarction (MI). This review focuses on the current use of antiplatelet agents in ST-segment elevation MI, a significant advancement in cardiovascular disease treatment.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Cardiovascular disease is a leading global cause of mortality.
  • Decreased myocardial infarction (MI) case-fatality rates in the US are attributed to improved acute MI treatments and secondary prevention.
  • Antiplatelet therapy is fundamental in managing MI.

Purpose of the Study:

  • To review the current landscape of antiplatelet therapy.
  • To specifically address its application in ST-segment elevation myocardial infarction (STEMI).

Main Methods:

  • Literature review of current antiplatelet therapies.
  • Focus on evidence pertaining to STEMI management.

Main Results:

  • Antiplatelet therapy remains a cornerstone in MI treatment.
  • Advances in secondary prevention have significantly reduced MI mortality.
  • Current strategies for STEMI involve specific antiplatelet regimens.

Conclusions:

  • Antiplatelet therapy is essential for STEMI patients.
  • Ongoing research and clinical practice evolve antiplatelet strategies for better outcomes in MI.

Keywords:
Antiplatelet agentsGP IIb/IIIa inhibitorsP2Y(12) inhibitorsST-segment elevation myocardial infarctionSTEMI

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