Related Experiment Video
Updated: Mar 1, 2026

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
Published on: March 31, 2023
Calcific Aortic Stenosis: Pathology and Role of Balloon Aortic Valvuloplasty
Usman Baber1, Annapoorna S Kini1, Pedro R Moreno1
1Cardiac Catheterization Laboratory, Mount Sinai Medical Center, One Gustave L. Levy Place, Box 1030, New York, NY 10029, USA.
Abstract:
Calcific aortic stenosis (AS) is a common expression of aortic valve disease and increases in prevalence with advancing age. Recent studies have shown that calcific deposition in aortic valve leaflets is an actively regulated process with many pathophysiologic similarities to atherosclerosis. Surgical valve replacement is the definitive treatment of calcific AS, but many patients do not undergo surgery because of prohibitive comorbidities or other high-risk features. Balloon aortic valvuloplasty remains an option for temporary palliation and symptomatic relief, and continues to serve as a bridge to aortic valve replacement in certain patients with AS requiring temporary hemodynamic stabilization.
More Related Videos
04:30Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
Published on: February 4, 2021
05:47Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
Published on: May 10, 2021
Related Concept Videos
Mitral Stenosis III: Medical Management
Aortic Regurgitation III: Medical Management
Aneurysm III: Interprofessional Care
Aortic Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests