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Updated: Mar 1, 2026

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019
Pathology of Saphenous Vein Grafts
Saami K Yazdani1, Fumiyuki Otsuka1, Masataka Nakano1
1Department of Cardiovascular Pathology, CVPath Institute, Inc. 19 Firstfield Road, Gaithersburg, MD 20878, USA.
Abstract:
Saphenous vein grafts (SVGs) are the most used conduits in coronary artery bypass graft (CABG) surgery; however, they are susceptible to accelerated atherosclerosis. Clinical studies have shown 10-year patency rates of SVG can be as low as 50% to 60%. This article highlights changes that are observed following CABG surgery using SVG, including intimal thickening to the development of atherosclerotic changes, and how these changes in vein graft are different from those observed in native atherosclerosis. It also discusses the role of risk factors that contribute to acceleration of SVG atherosclerosis.
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