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Updated: Mar 1, 2026

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
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Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

Published on: November 19, 2019

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Degenerated Saphenous Vein Graft Intervention: Should We Target the Native Vessel instead?

Corey Foster1, Alan Zajarias1

  • 1Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA.

Interventional Cardiology Clinics
|June 6, 2017
PubMed

Insights

Treating degenerated saphenous vein grafts (SVGs) with severe stenosis is challenging. This review examines SVG disease characteristics, risks, and strategies to improve outcomes for coronary interventions.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Interventional Cardiology

Background:

  • Degenerated saphenous vein grafts (SVGs) pose significant challenges in coronary interventions.
  • Both repeat coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) carry substantial risks for patients with SVG disease.

Purpose of the Study:

  • To review the optimal treatment strategies for severe stenosis in SVGs.
  • To analyze the characteristics of native versus SVG disease.
  • To identify risk factors and mitigation measures for periprocedural complications.

Main Methods:

  • Literature review and synthesis of existing studies on SVG interventions.
  • Analysis of clinical data regarding outcomes and complications.
  • Comparative assessment of different treatment modalities.

Main Results:

  • Lack of consensus on the optimal treatment strategy for SVG stenosis.
  • High periprocedural event rates associated with PCI in SVGs.
  • Significant operative mortality risks with repeat CABG.

Conclusions:

  • A comprehensive understanding of SVG disease is crucial for effective management.
  • Further research is needed to establish standardized treatment guidelines.
  • Mitigating periprocedural risks is paramount for improving patient outcomes.

Keywords:
Complex percutaneous coronary interventionEmbolic protection deviceSaphenous vein graft

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