Related Experiment Video

Updated: Mar 1, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

6.1K

Thrombectomy Devices in Coronary Intervention

Aaron Horne1, Matthews Chacko1

  • 1Division of Cardiology, Johns Hopkins Hospital, Johns Hopkins University, 1800 Orleans Street, Baltimore, MD 21287, USA.

Interventional Cardiology Clinics
|June 6, 2017
PubMed

Insights

Primary percutaneous coronary intervention is the preferred treatment for ST-elevation myocardial infarction (STEMI). Coronary thrombectomy use in STEMI is debated, but recent trials offer new insights for clinical practice.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Primary percutaneous coronary intervention (PCI) is the standard reperfusion therapy for ST-elevation myocardial infarction (STEMI).
  • The role of adjunctive coronary thrombectomy in STEMI management remains controversial due to limited historical data.
  • Recent trials like TAPAS have influenced the increasing use of thrombectomy in recent years.

Purpose of the Study:

  • To examine the existing trial evidence on coronary thrombectomy in STEMI.
  • To provide insights into the optimal management and application of thrombectomy in clinical practice.

Main Methods:

  • Review of relevant clinical trial evidence.
  • Analysis of data from trials including TOTAL, TASTE, and SMART PCI.
  • Examination of historical data and recent advancements in thrombectomy use.

Main Results:

  • The article synthesizes trial data to evaluate the efficacy and safety of coronary thrombectomy in STEMI.
  • Evidence suggests evolving perspectives on thrombectomy's role post-TAPAS trial.
  • Ongoing trials (TOTAL, TASTE, SMART PCI) are crucial for definitive conclusions.

Conclusions:

  • The optimal role of coronary thrombectomy in STEMI requires careful consideration of current and emerging trial evidence.
  • Clinical practice guidelines for STEMI management may be refined based on new data.
  • Further research and analysis are essential to standardize thrombectomy application in STEMI patients.

Keywords:
Percutaneous coronary interventionRheolysisST-elevation myocardial infarctionThrombectomy

More Related Videos

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug07:50

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

Published on: June 4, 2021

3.2K
New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation08:45

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

Published on: June 27, 2025

1.7K

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
423
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
557
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
346
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
443
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.6K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.1K