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Updated: Aug 13, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Skin to Skin: Transradial Carotid Angiography and Stenting
1Medical Faculty, Department of Interventional Cardiology, University Clinic of Cardiology, University of St Cyril & Methodius, Vodnjanska 17, Skopje 1000, Macedonia.
Insights
Carotid artery stenting (CAS) using the transradial approach offers a viable alternative to the transfemoral approach, especially for patients with complex aortic arches. This method may reduce access site complications and technical failures in carotid revascularization.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Carotid artery stenting (CAS) is an established treatment for significant carotid artery disease.
- The transfemoral approach (TFA) is the standard access route for CAS.
- TFA can be limited by peripheral vascular disease, anatomical variations, and complex aortic arches, leading to access site complications and technical failures.
Purpose of the Study:
- To evaluate the transradial approach (TRA) as an alternative access site for CAS.
- To determine if TRA can overcome the limitations associated with TFA, particularly in cases with complex aortic anatomy.
Main Methods:
- Review of existing literature and case studies comparing TFA and TRA for CAS.
- Analysis of complication rates and technical success related to access site and aortic arch complexity.
- Evaluation of patient factors influencing the choice of access site.
Main Results:
- Access site complications are the most frequent adverse events with TFA.
- Complex aortic arch anatomy poses significant challenges for TFA, impacting technical success.
- The transradial approach has demonstrated potential as a feasible alternative, particularly in challenging anatomies.
Conclusions:
- The transradial approach may be a valuable strategy to mitigate TFA-related complications in CAS.
- TRA offers a promising alternative for patients with complex aortic arches undergoing carotid revascularization.
- Further research is warranted to fully establish the role of TRA in CAS procedures.
Abstract:
Carotid artery stenting (CAS) is a proven alternative to carotid endarterectomy in patients with significant carotid disease. The femoral artery is the conventional access site for CAS procedures. However, this approach may be problematic because of peripheral vascular disease and anatomic variations. Access site complications are the most common adverse event after CAS from the transfemoral approach (TFA) and most technical failures are related to a complex aortic arch. The transradial approach has been evaluated to address the shortcomings of TFA. In cases involving a complex arch, transradial access may be a viable alternative strategy.
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