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Role of Parenteral Agents in Percutaneous Coronary Intervention for Stable Patients

David A Burke1, Duane S Pinto1

  • 1Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Deaconess Road, Palmer 415, Boston, MA 02215, USA.

Interventional Cardiology Clinics
|June 6, 2017
PubMed

Insights

Selecting the best anticoagulation and antiplatelet medications for percutaneous coronary intervention (PCI) requires balancing bleeding and ischemic risks. Further research is needed on newer drug combinations to optimize patient outcomes.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Percutaneous coronary intervention (PCI) commonly involves anticoagulation and antiplatelet therapy.
  • Numerous anticoagulant and antiplatelet agents are available, complicating treatment selection.

Purpose of the Study:

  • To review current data on anticoagulant and antiplatelet medications used in PCI.
  • To summarize guidelines for selecting optimal medical strategies based on individual patient risks.

Main Methods:

  • Literature review of existing data on anticoagulant and antiplatelet therapies for PCI.
  • Analysis of benefits and limitations of various drug classes.
  • Summary of current clinical guidelines.

Main Results:

  • Current strategies involve balancing ischemic and bleeding risks in patients undergoing PCI.
  • The optimal pairing of newer antiplatelet and anticoagulant agents requires further investigation.

Conclusions:

  • Individualized assessment of bleeding and ischemic risk is crucial for selecting PCI pharmacotherapy.
  • Ongoing research is necessary to understand the impact of novel drug combinations on PCI complications.

Keywords:
AbciximabAnticoagulationAntithrombinBivalirudinEptifibatideGlycoprotein IIb/IIIa receptor inhibitionHeparin

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