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Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures

Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures

Published on: March 12, 2018

Left Main Percutaneous Coronary Intervention.

Neil Ruparelia¹, Alaide Chieffo²

¹Department of Interventional Cardiology San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy; Department of Cardiology Imperial College, Du Cane Road, London W12 0HS, UK.

Interventional Cardiology Clinics

|June 6, 2017

Summary

This summary is machine-generated.

Percutaneous coronary intervention (PCI) is a viable treatment for unprotected left main stem (ULMS) disease, particularly in patients with favorable anatomy. Evidence supports PCI as an alternative to traditional bypass surgery.

Keywords:

Coronary artery bypass grafting Drug-eluting stents Guidelines Heart team Intravascular imaging Left main stem Percutaneous coronary intervention

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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

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Published on: April 17, 2021

Area of Science:

Cardiovascular Medicine
Interventional Cardiology

Background:

Unprotected left main stem (ULMS) disease affects 5-7% of patients undergoing coronary angiography.
Coronary artery bypass grafting (CABG) has been the traditional treatment for ULMS disease.

Purpose of the Study:

To review the evidence supporting percutaneous coronary intervention (PCI) for ULMS disease.
To discuss current guidelines and technical considerations for PCI in ULMS disease.

Main Methods:

Review of current literature and guidelines regarding PCI for ULMS disease.
Analysis of factors influencing treatment decisions, including coronary anatomy and SYNTAX scores.

Main Results:

PCI is increasingly recognized as a feasible alternative to CABG for select ULMS disease patients.
Advances in stent technology, pharmacotherapy, and operator experience have improved PCI outcomes.
Favorable coronary anatomy and low-to-intermediate SYNTAX scores favor PCI as a treatment option.

Conclusions:

PCI offers a viable treatment option for unprotected left main stem disease in carefully selected patients.
The decision between PCI and CABG should consider anatomical complexity and patient-specific factors.