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Updated: Mar 1, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Intravenous and Oral Hydration: Approaches, Principles, and Differing Regimens
Igor Rojkovskiy1, Richard Solomon1
1Division of Nephrology and Hypertension, Fletcher Allen Health Care, University of Vermont College of Medicine, UHC 2309, 1 South Prospect Street, Burlington, VT 05401, USA.
Abstract:
Prevention of contrast-induced nephropathy is founded on minimizing the pathophysiologic consequences of contrast media (CM) interacting with a vulnerable kidney. In this article, the rationale for administering fluid (oral or intravenous) is discussed, and the clinical trials exploring different protocols are reviewed. A benefit from administration of fluids before CM exposure, which corrects volume depletion and increases urine output, can be expected. Forced diuresis without adequate volume replacement is deleterious.
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