Related Experiment Video

Updated: Mar 1, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.6K

Update in the management of pediatric psoriasis

Jennifer Aileen Ang Tangtatco1, Irene Lara-Corrales

  • 1aSection of Dermatology, Division of Paediatric Medicine, The Hospital for Sick Children bDepartment of Paediatrics, University of Toronto, Toronto, Ontario, Canada.

Current Opinion in Pediatrics
|June 6, 2017
PubMed

Insights

Pediatric psoriasis management is evolving, highlighting new disease links and advanced treatments like biologics. Understanding these updates is crucial for addressing this chronic inflammatory skin condition in children.

Area of Science:

  • Dermatology
  • Pediatrics
  • Immunology

Background:

  • Psoriasis in children presents unique management challenges.
  • It is a multifactorial, chronic, inflammatory skin disease.

Purpose of the Study:

  • To provide a framework for managing pediatric psoriasis.
  • To highlight new disease associations and innovative treatments.
  • To challenge current approaches to pediatric psoriasis.

Main Methods:

  • Literature review focusing on recent publications.
  • Analysis of new disease associations and comorbidities.
  • Evaluation of emerging treatment modalities, including biologics.

Main Results:

  • Growing evidence links pediatric psoriasis with comorbidities, suggesting a systemic disease.
  • Newer medications, including biologics, are being investigated for pediatric use.
  • Recent studies report on the efficacy and safety of biologics in pediatric patients.

Conclusions:

  • Enhanced understanding of risks associated with untreated pediatric psoriasis.
  • Improved awareness of benefits and risks of novel therapeutic options.
  • Provides a framework for current and future management strategies.
Abstract

More Related Videos

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

966
A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

1.3K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
338
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
293
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
392
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
387
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
434
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.9K