Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

5.7K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
5.7K
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

2.5K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Overexpression of Short Variant Form of New Kelch Family Protein Leads to Erythroid and Megakaryocyte Dysplasia by Targeting Megakaryocyte-Erythroid Progenitors.

DNA and cell biology·2018
Same author

Height, VKORC1 1173, and CYP2C9 Genotypes Determine Warfarin Dose for Pediatric Patients with Kawasaki Disease in Southwest China.

Pediatric cardiology·2018
Same author

Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies.

International journal of nanomedicine·2018
Same author

Improving dispersive property, biocompatibility and targeting gene transfection of graphene oxide by covalent attachment of polyamidoamine dendrimer and glycyrrhetinic acid.

Colloids and surfaces. B, Biointerfaces·2018
Same author

Zwitterion Functionalized Silica Nanoparticle Coatings: The Effect of Particle Size on Protein, Bacteria, and Fungal Spore Adhesion.

Langmuir : the ACS journal of surfaces and colloids·2018
Same author

<i>Radix Rehmanniae</i> Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-Derived Nitrative Damage.

Frontiers in physiology·2018
Same journal

PBAE nanoparticle-mediated delivery of ASCL1 and NGN2 genes for astroglia-to-neuron reprogramming to remodel glial scar for spinal cord injury repair.

Stem cell research & therapy·2026
Same journal

Lipoaspirate-derived secretome restores redox homeostasis to attenuate pathological scar formation.

Stem cell research & therapy·2026
Same journal

Identification and enrichment of human retinal organoid-derived red/green cone-competent precursors with enhanced axon dynamics.

Stem cell research & therapy·2026
Same journal

PTGIS inhibited osteogenic and promoted angiogenic differentiation of bone marrow mesenchymal stem cells via endoplasmic reticulum stress mediated PI3K/AKT signaling.

Stem cell research & therapy·2026
Same journal

ITGA1 promotes osteogenic differentiation of human periodontal ligament stem cells via FAK-mediated PI3K-Akt activation.

Stem cell research & therapy·2026
Same journal

Therapeutic potential of mesenchymal stem cell-derived apoptotic vesicles in liver fibrosis: targeting the IGFBP3/PI3K-AKT axis via miR-409-3p.

Stem cell research & therapy·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
07:24

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus

Published on: January 23, 2018

10.9K

Mesenchymal stem cells for treating autoimmune dacryoadenitis.

Xiaoxiao Lu1, Xilian Wang2, Hong Nian1

  • 1Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute & Tianjin Medical University School of Optometry and Ophthalmology, No.251 Fukang Road, Nankai District, Tianjin, 300384, People's Republic of China.

Stem Cell Research & Therapy
|June 7, 2017
PubMed
Summary
This summary is machine-generated.

Mesenchymal stem cells (MSCs) show promise for treating autoimmune dacryoadenitis, offering potential beyond current palliative therapies. Research is exploring MSCs

Keywords:
Autoimmune dacryoadenitisImmunomodulationMesenchymal stem cells

More Related Videos

Author Spotlight: Advancing Treatment Approaches with Adipose-Derived Stem Cells
04:53

Author Spotlight: Advancing Treatment Approaches with Adipose-Derived Stem Cells

Published on: January 12, 2024

1.6K
Magnetic-Activated Cell Sorting Strategies to Isolate and Purify Synovial Fluid-Derived Mesenchymal Stem Cells from a Rabbit Model
10:20

Magnetic-Activated Cell Sorting Strategies to Isolate and Purify Synovial Fluid-Derived Mesenchymal Stem Cells from a Rabbit Model

Published on: August 10, 2018

11.8K

Related Experiment Videos

Last Updated: Mar 1, 2026

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
07:24

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus

Published on: January 23, 2018

10.9K
Author Spotlight: Advancing Treatment Approaches with Adipose-Derived Stem Cells
04:53

Author Spotlight: Advancing Treatment Approaches with Adipose-Derived Stem Cells

Published on: January 12, 2024

1.6K
Magnetic-Activated Cell Sorting Strategies to Isolate and Purify Synovial Fluid-Derived Mesenchymal Stem Cells from a Rabbit Model
10:20

Magnetic-Activated Cell Sorting Strategies to Isolate and Purify Synovial Fluid-Derived Mesenchymal Stem Cells from a Rabbit Model

Published on: August 10, 2018

11.8K

Area of Science:

  • Immunology and Regenerative Medicine

Background:

  • Autoimmune dacryoadenitis, exemplified by Sjögren syndrome, involves complex multifactorial diseases where lacrimal gland inflammation is central to pathogenesis.
  • Current treatments like artificial tears, anti-inflammatory drugs, punctual occlusion, and immunosuppressive drugs offer only palliative relief and are associated with limiting adverse effects.
  • There is a critical need for effective and safe treatments for autoimmune dacryoadenitis.

Purpose of the Study:

  • To review recent advances in the application of mesenchymal stem cells (MSCs) for the treatment of autoimmune dacryoadenitis.
  • To highlight the potential of MSCs as a therapeutic strategy for autoimmune dacryoadenitis, addressing the limitations of current treatments.

Main Methods:

  • Review of existing scientific literature on mesenchymal stem cell therapy for autoimmune diseases, with a focus on autoimmune dacryoadenitis.
  • Analysis of studies investigating the immunosuppressive, tissue repair, and differentiation capabilities of MSCs in the context of autoimmune conditions.

Main Results:

  • Mesenchymal stem cells (MSCs) possess inherent immunosuppressive properties, tissue repair functions, and differentiation capabilities, making them a promising therapeutic candidate.
  • While MSCs have shown efficacy in other autoimmune diseases like uveitis, inflammatory bowel disease, and arthritis, their specific efficacy in autoimmune dacryoadenitis requires further robust investigation.
  • The review synthesizes current research, identifying key findings and areas for future study regarding MSCs for autoimmune dacryoadenitis.

Conclusions:

  • Mesenchymal stem cells (MSCs) represent a potential therapeutic avenue for autoimmune dacryoadenitis, offering a more targeted approach than current palliative treatments.
  • Further research is essential to unequivocally establish the efficacy and safety of MSCs for treating autoimmune dacryoadenitis, building upon their known properties and successes in other autoimmune conditions.