Related Experiment Video

Updated: Mar 1, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.5K

Long-term Clinical Outcomes of Kidney Re-transplantation

S M Yeo1, Y Kim1, S S Kang2

  • 1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea.

Transplantation Proceedings
|June 7, 2017
PubMed
Abstract

Insights

Second kidney transplantation (2nd KT) shows good patient and graft survival rates despite higher immunological risks. Long-term outcomes depend on factors from the first kidney transplant, necessitating careful immunologic monitoring.

Area of Science:

  • Nephrology
  • Transplantation Immunology

Background:

  • Kidney re-transplantation often carries higher immunological risks compared to first-time transplants.
  • Increasing organ shortages and waiting lists highlight the need for understanding long-term re-transplantation outcomes.
  • Published data on re-transplantation outcomes remain limited, underscoring the value of long-term experience reports.

Purpose of the Study:

  • To evaluate the long-term outcomes of second kidney transplantation (2nd KT).
  • To analyze factors influencing graft survival in patients undergoing a second kidney transplant.

Main Methods:

  • A retrospective analysis of 105 second kidney transplantations (2nd KT) performed between 1982 and 2016.
  • Data included living donor and deceased donor kidney transplantations, with patient and graft survival rates assessed over 1, 5, and 10 years.

Main Results:

  • Patient survival rates at 1, 5, and 10 years were 100%, 97.2%, and 90.7%, respectively.
  • Graft survival rates at 1, 5, and 10 years were 97.0%, 94.6%, and 71.5%, respectively.
  • The primary cause of graft failure was chronic rejection (60%); first transplant factors significantly impacted 2nd KT outcomes.

Conclusions:

  • Second kidney transplantation achieved reasonable patient and graft survival rates.
  • Careful monitoring of immunologic risk is crucial for optimizing outcomes in kidney re-transplantation.

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.3K
Mouse Kidney Transplantation: Models of Allograft Rejection16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

21.8K

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
572
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
599
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
1.1K
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
454
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
863
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
391