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Castleman Disease Presenting as an Abdominal Mass
Farnaz Shariati1, Elizabeth Verter2, Wendy Chang2
1Department of Internal Medicine, Ochsner Health System, New Orleans, LA.
Insights
We present a rare case of abdominal Castleman disease (CD) in a 66-year-old man. Surgical resection confirmed the hyaline vascular variant of CD, highlighting this condition
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Unicentric Castleman disease (UCD) is a rare lymphoproliferative disorder.
- Abdominal UCD is exceptionally rare, accounting for only 15% of all cases.
- Symptoms can be vague, including abdominal pain, leading to diagnostic challenges.
Abstract:
Unicentric Castleman disease is a rare condition of lymphoid hyperplasia, of which only 15% of cases occur in the abdomen. We report a 66-year-old man who presented with complaints of abdominal pain. Computed tomography scans revealed nephrolithiasis and a homogeneous calcified mass between the pancreas and stomach and several para-pancreatic nodes. Direct visualization during exploratory laparotomy revealed a mass on the lesser curvature of the stomach. Pyloromyotomy and mass resection were performed. Biopsy showed reactive lymphoid hyperplasia consistent with the hyaline vascular variant of Castleman disease.
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