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Precision Medicine for Heart Failure with Preserved Ejection Fraction: An Overview
1Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. sanjiv.shah@northwestern.edu.
Journal of Cardiovascular Translational Research
|June 7, 2017
Summary
Heart failure with preserved ejection fraction (HFpEF) requires a precision medicine approach due to its heterogeneity. This special issue explores advanced methods for targeted HFpEF classification and treatment.
Area of Science:
- Cardiovascular Medicine
- Translational Research
- Precision Medicine
Background:
- Heart failure with preserved ejection fraction (HFpEF) lacks proven therapies.
- HFpEF is recognized as a heterogeneous disorder.
- A one-size-fits-all treatment approach is unlikely to be effective for HFpEF.
Purpose of the Study:
- To introduce a special theme issue on precision medicine in HFpEF.
- To highlight the need for targeted approaches in HFpEF classification and treatment.
- To stimulate further research and clinical application of precision medicine in HFpEF.
Main Methods:
- Compilation of papers covering various aspects of precision medicine in HFpEF.
- Exploration of automated patient identification, machine learning, and genomics.
- Discussion of novel molecular approaches, deep phenotyping, and clinical trial designs.
Main Results:
- The collected papers provide a comprehensive overview of precision medicine strategies for HFpEF.
- The issue covers advanced computational and biological methods for HFpEF research.
- Innovative clinical trial designs are presented to facilitate precision medicine advancements.
Conclusions:
- Precision medicine offers a promising avenue for advancing HFpEF treatment.
- The compendium aims to guide future research and clinical practice in HFpEF.
- A targeted approach is essential for improving outcomes in heterogeneous HFpEF populations.
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