Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relationship between pork consumption and cirrhosis.

A A Nanji, S W French

    Lancet (London, England)
    |March 23, 1985
    PubMed
    Summary

    Pork consumption shows a significant correlation with cirrhosis mortality, especially in regions with low alcohol intake. This suggests pork may be a key dietary factor in cirrhosis development, independent of alcohol.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The role of the IL-8 signaling pathway in the infiltration of granulocytes into the livers of patients with alcoholic hepatitis.

    Experimental and molecular pathology·2017
    Same author

    Over expression of proteins that alter the intracellular signaling pathways in the cytoplasm of the liver cells forming Mallory-Denk bodies.

    Experimental and molecular pathology·2017
    Same author

    Alcoholic steatohepatitis (ASH) causes more UPR-ER stress than non-alcoholic steatohepatitis (NASH).

    Experimental and molecular pathology·2016
    Same author

    Upregulation of autophagy components in alcoholic hepatitis and nonalcoholic steatohepatitis.

    Experimental and molecular pathology·2016
    Same author

    What are the mechanisms of regeneration inhibition in alcoholic hepatitis?

    Experimental and molecular pathology·2016
    Same author

    The mechanisms of Mallory-Denk body formation are similar to the formation of aggresomes in Alzheimer's disease and other neurodegenerative disorders.

    Experimental and molecular pathology·2016

    Area of Science:

    • Epidemiology
    • Nutritional Science
    • Gastroenterology

    Background:

    • Cirrhosis mortality rates vary globally.
    • Dietary factors are implicated in liver disease.
    • The role of specific food items, like pork, in cirrhosis is not fully understood.

    Purpose of the Study:

    • To investigate the association between per-caput consumption of total fat, beef, and pork and mortality rates for cirrhosis across various countries.
    • To explore the relationship between alcohol consumption, pork consumption, and cirrhosis mortality.
    • To examine these relationships in specific regions with varying alcohol consumption levels.

    Main Methods:

    • Cross-sectional study design comparing per-caput food consumption data with cirrhosis mortality rates.
    • Correlation analysis was used to assess the relationships between dietary factors (total fat, beef, pork, alcohol) and cirrhosis mortality.
    • Analysis was stratified by alcohol consumption levels and examined within Canadian provinces.

    Main Results:

    • A significant positive correlation was found between alcohol consumption and cirrhosis mortality (r=0.64, p<0.01).
    • Pork consumption also showed a significant positive correlation with cirrhosis mortality (r=0.40, p<0.05).
    • The combined effect of alcohol and pork consumption demonstrated a highly significant correlation with cirrhosis mortality (r=0.98, p<0.001).
    • In areas with low alcohol consumption, pork consumption remained significantly correlated with cirrhosis mortality, whereas alcohol consumption did not show a correlation.
    • A similar pattern was observed in Canadian provinces, with a significant correlation between pork and cirrhosis mortality, but not alcohol and cirrhosis mortality.

    Conclusions:

    • Pork consumption is significantly associated with cirrhosis mortality, particularly in populations with low alcohol intake.
    • The combined consumption of alcohol and pork shows a synergistic effect on cirrhosis mortality.
    • Dietary factors, specifically pork, may play a crucial role in the etiology of cirrhosis, independent of alcohol consumption.

    Related Experiment Videos