Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Professor Frowein.

Journal of neurological surgery. Part A, Central European neurosurgery·2021

Same author

Current Practice of Neurosurgical Teleconsultation in Germany.

Journal of neurological surgery. Part A, Central European neurosurgery·2020

Same author

Collision of Priorities in Posttraumatic Coma and Suspected Multiple Injuries: A Prospective Multicenter Trial.

Journal of neurological surgery. Part A, Central European neurosurgery·2020

Same author

Resolution of Brainstem Edema after Neurosurgical Occlusion of Dural Arteriovenous Fistulas of the Craniocervical Junction: Report of Three Cases and Review.

Journal of neurological surgery. Part A, Central European neurosurgery·2019

Same author

Pertinent Points Need to Be More Convincingly Stated.

Deutsches Arzteblatt international·2019

Same author

In Reply.

Deutsches Arzteblatt international·2017

Search research articles

Related Experiment Video

Updated: Mar 1, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

Coma After Acute Head Injury.

Raimund Firsching¹

¹Universitätsklinik für Neurochirurgie, Magdeburg.

Deutsches Arzteblatt International

|June 8, 2017

Summary

Immediate treatment for traumatic brain injury (TBI) is crucial. Prompt cranial computed tomography and surgical intervention for intracranial hematomas can be life-saving, significantly impacting patient prognosis.

Area of Science:

Neurology
Neurosurgery
Trauma Care

Background:

Coma following acute head injury necessitates urgent medical attention.
Traumatic brain injury (TBI) affects approximately 250,000 individuals in Germany annually.
Evolving knowledge requires continuous updates to TBI treatment guidelines.

Purpose of the Study:

To review current treatment recommendations for post-traumatic coma.
To outline prognostic factors influencing outcomes in head-injured patients.
To discuss the pathophysiology of coma after acute head injury.

Main Methods:

Literature review based on a 2015 German guideline for head injury.
Selective PubMed search for publications on post-traumatic coma.
Analysis of prognostic factors and pathophysiology.

More Related Videos

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

A Repetitive Concussive Head Injury Model in Mice

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

Related Experiment Videos

Last Updated: Mar 1, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

Published on: April 11, 2025

A Repetitive Concussive Head Injury Model in Mice

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

Main Results:

Cranial computed tomography (CT) is essential for identifying surgically treatable intracranial injuries.
Intracranial hematomas with mass effect require immediate surgical intervention.
Prognosis is linked to age, coma duration, neurological deficits, and injury location, with high mortality rates for severe neurological signs.

Conclusions:

Brain tissue has limited tolerance to ischemia and elevated pressure.
Urgent evaluation of comatose head-injured patients is vital.
Surgical options like hematoma removal or decompressive hemicraniectomy may improve outcomes.