Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

694
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
694
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

898
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
898
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

441
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
441
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

556
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
556
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

518
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
518
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

367
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
367

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Trends and Outcomes in Transcatheter Aortic Valve Implantation: a report from the SwissTAVI Registry.

Cardiovascular intervention and therapeutics·2026
Same author

Comparison of Cardiac Troponin T and I: Impact on Definitions of Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting.

Journal of the American Heart Association·2026
Same author

Complex hybrid management of severe aortic stenosis and aortic arch disease in a nonagenarian: a case report.

European heart journal. Case reports·2026
Same author

Treatment of infected endografts after thoracic endovascular aortic repair: a systematic review.

Science progress·2026
Same author

The Role of Packaged Red Blood Cells Administration on Long-term Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation.

The Canadian journal of cardiology·2025
Same author

EACTS Expert Consensus Statement on the Ross Procedure in Adult Patients.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2025

Related Experiment Video

Updated: Mar 1, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.1K

Aortic Valve Pathology as a Predictive Factor for Acute Aortic Dissection.

Denis Berdajs1, Selim Mosbahi2, Enrico Ferrari2

  • 1Department of Cardiac Surgery, University Hospital Basel, Basel; Department of Surgery and Anesthesiology, Cardiovascular Research, University Hospital Lausanne, Lausanne.

The Annals of Thoracic Surgery
|June 8, 2017
PubMed
Summary
This summary is machine-generated.

Aortic valve pathology can trigger aortic dissection. AV insufficiency causes low shear stress and turbulent flow, while AV stenosis leads to high shear stress and pressure, potentially causing type A dissection.

More Related Videos

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
07:10

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury

Published on: March 31, 2023

1.6K
Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

4.5K

Related Experiment Videos

Last Updated: Mar 1, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.1K
A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
07:10

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury

Published on: March 31, 2023

1.6K
Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

4.5K

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • Aortic valve (AV) pathology is investigated as a potential cause of acute aortic dissection.
  • The study evaluates the impact of AV pathology on local hemodynamic conditions.

Purpose of the Study:

  • To determine if aortic valve pathology influences hemodynamic factors that may trigger aortic dissection.
  • To differentiate the hemodynamic effects of aortic valve stenosis versus insufficiency.

Main Methods:

  • A 4-D computed fluid dynamic model of the aorta was developed.
  • Aortic valve stenosis and insufficiency were experimentally induced.
  • High-fidelity microsonometric crystals recorded aortic root geometry and pressure.

Main Results:

  • Aortic root expansion was greater in AV insufficiency compared to AV stenosis.
  • AV insufficiency resulted in low shear stress, turbulent flow, and high pressure in the ascending aorta and aortic arch.
  • AV stenosis showed high shear stress and elevated pressure in the ascending aorta and brachiocephalic trunk bifurcation.

Conclusions:

  • Low shear stress and turbulent flow in AV insufficiency correlate with typical dissection entry sites.
  • High shear stress and pressure in AV stenosis may initiate vessel dilation, aneurysm formation, and intimal tears characteristic of type A dissection.