Related Experiment Video
Updated: Mar 1, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Primary Angioplasty for the Treatment of Acute ST Elevated Myocardial Infarction: Single Centre Experience
1Dr Kaisar Nasrullah Khan, Department of Cardiology, United Hospital Limited (UHL), Gulshan, Dhaka, Banglaldesh.
Insights
Primary angioplasty is a safe and effective reperfusion strategy for acute myocardial infarction, achieving high success rates. This study demonstrates its feasibility and positive outcomes in a local hospital setting.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Myocardial Infarction Management
Background:
- Primary angioplasty is the recommended reperfusion strategy for acute myocardial infarction (AMI) globally.
- It offers superior reperfusion rates (over 90%) compared to thrombolytics (60-70%).
Purpose of the Study:
- To evaluate the feasibility, safety, and outcomes of primary angioplasty in patients with AMI at United Hospital.
- To assess the procedural success and complication rates of primary angioplasty in a specific healthcare setting.
Main Methods:
- Retrospective observational study of 114 consecutive AMI patients treated with primary angioplasty between March 2007 and January 2011.
- Exclusion criteria included presentation beyond 12 hours, cardiogenic shock, or pre-procedure intubation.
- Data collected on patient demographics, risk factors, involved coronary arteries, door-to-balloon times, stent usage, adjunctive medications, complications, and survival rates.
Main Results:
- The study included 114 patients, predominantly male (89%), with a mean age range of 30-90 years.
- Common comorbidities included hypertension (58.4%), diabetes (41.5%), and dyslipidemia (43.5%).
- The Left Anterior Descending (LAD) artery was most frequently involved (57%). Door-to-balloon times ranged from 23 to 184 minutes. Overall survival was high at 97.9%, with reported complications including arrhythmias (24%), hypotension (18%), and no-flow/slow-flow phenomenon (45%).
Conclusions:
- Primary angioplasty is a feasible and safe reperfusion method for acute myocardial infarction in the studied center.
- The procedure demonstrated high survival rates, supporting its implementation in similar healthcare settings.
- Initial experiences suggest confidence in performing primary angioplasty for eligible patients, contributing to improved AMI management.
Abstract:
Worldwide primary angioplasty is a recommended strategy of reperfusion in patient with acute myocardial infarction as because it ensures reperfusion of the infarct-related vessels more than 90% whereas, with thrombolytics it is only 60-70%. This retrospective observational study includes all patients treated with primary angioplasty at United Hospital from Between March 2007 to January 2011. Total 114 consecutive patients with acute myocardial infarction were treated with primary angioplasty included. Those presented beyond 12 hours of onset of chest pain, in cardiogenic shock, resuscitate and intubated before the procedure were excluded from the study. Majority (89%) of the patient were male, age was minimum 30 years and maximum 90 years, 41.5% were diabetics, 58.4% were hypertensive, 43.5% were dyslipidaemic, 17% were smoker, 29.3% with positive family history. Fifty seven percent patients presented with anterior MI , 42 % with inferior MI and 1% with lateral MI. Left anterior descending (LAD) is the most common vessel involved (57%), followed by Right coronary artery (RCA) 31%, Left circumflex artery (LCX) 8 %, Ramus 1.3% and Graft vessel 2.7%. Our door to balloon time was minimum 23 min, maximum 184 min. We used drug eluting stents for most of the patients, GP IIb- IIIa receptor blockers used in 50% cases and thrombus suction device were used when indicated. We faced complications like arrhythmias in 24%, hypotension in18%, no flow or slow flow in 45%, cardiac arrest in 3% and coronary perforation in 1%. Our overall survival was 97.9%. Primary angioplasty is an emerging area in context of our country. Many of the new centers start this novel strategy which helps to save many lives Primary angioplasty is feasible and safe method of reperfusion in patient with acute myocardial infarction in our center. With the help of our initial experience we can perform PAMI with confidence to those who can afford and who need most.
More Related Videos
09:21Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Angina IV: Management