Association of Relationship between Periodontal Disease and Cardiovascular Disease

Area of Science:

• Periodontology
• Cardiology
• Biochemistry

Background:

• Previous research suggests a link between periodontal disease (PD) and cardiovascular disease (CVD).
• Understanding this relationship is crucial for public health and clinical practice.

Purpose of the Study:

• To investigate the correlation between periodontal disease and cardiovascular disease markers.
• To assess specific indicators of both conditions in a patient cohort.

Main Methods:

• 186 patients were divided into cardiac disease (n=100) and control (n=86) groups.
• Periodontal health was assessed using plaque index, calculus index, gingival and periodontal index (PDI).
• Cardiovascular disease markers included LDL, HDL, total cholesterol, and C-reactive protein (CRP).

Main Results:

• A significant increase in CRP levels was observed in cardiac patients with periodontal disease (Group A1) compared to controls.
• Cardiac groups showed significantly higher CRP levels overall compared to non-cardiac groups.
• No significant changes were found in lipid profile markers (LDL, HDL, total cholesterol).
• Periodontal Disease Index (PDI) was higher in Group A1 and overall in cardiac groups.

Conclusions:

• This study found no significant correlation between periodontal disease and cardiovascular disease.
• Elevated CRP in cardiac patients may be influenced by factors other than periodontal disease.
• The use of statins in some cardiac patients might have confounded the results regarding lipid profiles.