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Radiation-associated colon cancer: A case report
Kazuhito Sasaki1, Soichiro Ishihara1, Keisuke Hata1
1Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Molecular and Clinical Oncology
|June 8, 2017
Summary
Radiation-associated colon cancer is rare. This case highlights a 48-year-old man who developed two colon tumors 19 years after preoperative radiotherapy and rectal surgery, emphasizing the need for surveillance.
Area of Science:
- Oncology
- Gastroenterology
- Radiation Oncology
Background:
- Radiation-associated colon cancer is an uncommon condition.
- Preoperative radiotherapy for rectal cancer can increase the risk of secondary malignancies.
- Long-term surveillance is crucial for patients treated with radiotherapy.
Purpose of the Study:
- To describe a rare case of radiation-associated colon cancer.
- To highlight the clinical characteristics and management of this condition.
- To emphasize the importance of colonoscopic surveillance in at-risk patients.
Main Methods:
- Case report of a 48-year-old male patient.
- Review of patient history including low anterior resection and preoperative radiotherapy (50 Gy).
- Diagnostic colonoscopy, computed tomography, magnetic resonance imaging, and surgical resection.
Main Results:
- The patient presented with two well-differentiated adenocarcinoma tumors in the sigmoid colon 19 years post-radiotherapy.
- Colonoscopy revealed additional flat polyps (tubular adenomas).
- Surgical resection (laparoscopic-assisted intersphincteric resection) was performed without complications.
Conclusions:
- Colonoscopic surveillance may be indicated for rectal cancer patients receiving preoperative radiotherapy.
- Early detection and management are crucial for radiation-associated colon cancer.
- Long-standing radiation-induced colitis may increase the risk.
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