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Updated: Mar 1, 2026

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
Iodine-catalyzed sulfenylation of pyrazolones using dimethyl sulfoxide as an oxidant
Yogesh Siddaraju1, Kandikere Ramaiah Prabhu
1Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India. prabhu@orgchem.iisc.ernet.in.
Abstract:
An iodine catalyzed sulfenylation of pyrazolones with a diverse range of heterocyclic thiols, heterocyclic thiones and disulfides has been described using dimethyl sulfoxide as an oxidant, which is an inexpensive, readily available and green oxidant. The present methodology exhibits a wide range of substrate scope and targeted products were obtained in good to excellent yields under metal-free conditions in a short duration. This methodology provides a simple process for the formation of C-S bonds through the thioetherification of pyrazolones.
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