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Ana García García de Paredes, Luis Téllez Villajos, Lara Aguilera Castro

    Acta Gastroenterologica Latinoamericana
    |June 8, 2017
    PubMed
    Summary

    Syphilis can cause unusual liver disease, presenting as acute cholestatic hepatitis. Early diagnosis and antibiotic treatment are crucial for recovery, especially in at-risk individuals.

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    Area of Science:

    • Hepatology
    • Infectious Diseases
    • Internal Medicine

    Background:

    • Syphilis is a chronic systemic infection with diverse clinical presentations.
    • Liver involvement in syphilis is rare, primarily seen in HIV-positive individuals.

    Observation:

    • A case report of a 42-year-old immunocompetent male with acute cholestatic hepatitis.
    • The patient's liver disease was the sole manifestation of syphilis, complicating diagnosis.

    Findings:

    • Diagnosis of luetic hepatitis was established.
    • Syphilis was identified as the cause of acute cholestatic hepatitis in an immunocompetent patient.

    Implications:

    • Highlights the importance of considering syphilis in the differential diagnosis of abnormal liver function tests.
    • Emphasizes that syphilis can present solely with liver disease, even in immunocompetent individuals.
    • Underscores the curability of luetic hepatitis with appropriate antibiotic therapy.