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Related Experiment Video

Updated: Mar 1, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Large colloid drusen analyzed with structural en face optical coherence tomography.

Nathália Corbelli Roberti¹, João Rafael de Oliveira Dias², Eduardo Amorim Novais²

¹Department of Ophthalmology, Hospital Brigadeiro, São Paulo, SP, Brazil.

Arquivos Brasileiros De Oftalmologia

|June 8, 2017

Summary

Large colloid drusen (LCD) are RPE deposits causing vision loss. En face OCT imaging reveals characteristic structural changes and provides insights into LCD progression and associated visual impairment.

Area of Science:

Ophthalmology
Retinal Imaging
Medical Diagnostics

Background:

Drusen are extracellular deposits beneath the retinal pigment epithelium (RPE).

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Last Updated: Mar 1, 2026

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Large colloid drusen (LCD) present as dome-shaped RPE detachments with overlying ellipsoid zone attenuation.

LCD can lead to progressive vision impairment.