Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosurgery01:30

Psychosurgery

2.1K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
2.1K
Brain Imaging01:14

Brain Imaging

799
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
799
Long-term Potentiation01:25

Long-term Potentiation

3.7K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paul Bouts and the Short Life of Psychognomy in Brazil.

Arquivos de neuro-psiquiatria·2022
Same author

Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials.

Nutrition reviews·2022
Same author

Publisher Correction: Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA.

Communications biology·2021
Same author

Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA.

Communications biology·2021
Same author

Endovascular closure of patent foramen ovale: a critical appraisal of published trials.

Arquivos de neuro-psiquiatria·2019
Same author

Lampião, Lages, Lombroso: the autopsy of the bandit king of the Brazilian backlands.

Arquivos de neuro-psiquiatria·2019

Related Experiment Video

Updated: Mar 1, 2026

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships
06:05

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships

Published on: April 20, 2022

2.3K

Evolving story: trepanation and self-trepanation to enhance brain function.

Charles André1

  • 1Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Departamento de Neurologia, Rio de Janeiro RJ, Brasil.

Arquivos De Neuro-Psiquiatria
|June 8, 2017
PubMed
Summary

Trepanation, the practice of drilling a hole in the skull, gained traction in the 1960s as a method for enhancing mental well-being. Its future is uncertain as key proponents age.

More Related Videos

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy
04:26

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy

Published on: July 5, 2024

1.1K
Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

9.3K

Related Experiment Videos

Last Updated: Mar 1, 2026

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships
06:05

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships

Published on: April 20, 2022

2.3K
Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy
04:26

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy

Published on: July 5, 2024

1.1K
Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

9.3K

Area of Science:

  • Anthropology
  • History of Medicine
  • Cultural Studies

Background:

  • Trepanation resurged in the 1960s, promoted by a Dutch student advocating it for increased cerebral blood flow.
  • The practice was popularized through self-experimentation, publications, films, and institutional promotion.

Discussion:

  • The movement involved self-trepanation, collaborative research with Russian scientists, and the establishment of organizations.
  • Promotional activities included organizing trips for individuals seeking the procedure in Central and South America.

Key Insights:

  • Dozens of individuals currently seek trepanation for spiritualization and enhanced mental capabilities.
  • The practice is linked to a counter-culture movement influenced by psychoactive drug use and alternative health beliefs.

Outlook:

  • The long-term future of the trepanation phenomenon remains uncertain due to the aging demographic of its main proponents.
  • Continued interest may depend on new generations adopting or adapting the practice.