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Related Concept Videos

Pore Size Distribution01:23

Pore Size Distribution

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In concrete, the pore size distribution significantly influences the material's properties. Capillary pores, markedly larger than gel pores, form a vast network within partially hydrated cement paste, reducing the concrete's strength and increasing its permeability. This heightened permeability leads to a greater risk of damage from environmental factors like freeze-thaw cycles and chemical attacks, with the extent of vulnerability also being tied to the water-to-cement ratio.
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Geometrical Effect in 2D Nanopores.

Ke Liu, Martina Lihter, Aditya Sarathy

  • 1Department of Engineering, University of Cambridge , JJ Thomson Avenue, CB3 0FA Cambridge, United Kingdom.

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|June 9, 2017
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Summary

Researchers explored how nanopore shape affects DNA translocation. They found that non-circular nanopores, like triangular ones, significantly alter ion flow, leading to a geometry-dependent ion scattering effect.

Keywords:
2D materialsSolid-state nanoporeshexagonal boron nitride (h-BN)high-resolution transmission electron microscopy (HRTEM)ion transportmolybdenum disulfide (MoS2)

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Biophysics

Background:

  • Solid-state nanopores lack precise geometric control compared to biological protein nanopores.
  • Experimentally formed solid-state nanopores typically exhibit a circular shape.

Purpose of the Study:

  • Investigate the impact of nanopore geometry on ion blockage during DNA translocation.
  • Compare triangular (h-BN) and circular (MoS2) nanopore shapes.

Main Methods:

  • Fabrication and experimentation with triangular and circular solid-state nanopores.
  • Measurement of ionic blockage during DNA translocation.
  • Development and application of a modified ionic blockage model.

Main Results:

  • Observed a significant geometry-dependent ion scattering effect.
  • Validated experimental findings with a modified ionic blockage model.
  • Demonstrated that pore geometry influences ion permeability and scattering.

Conclusions:

  • Nanopore shape critically affects ion scattering and blockage during DNA translocation.
  • A modified ionic blockage model accounting for geometric variations improves accuracy.
  • Findings guide the rational design of two-dimensional (2D) nanopores for various applications.