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Marginal Shape Deep Learning: Applications to Pediatric Lung Field Segmentation.

Awais Mansoor1, Juan J Cerrolaza1, Geovanny Perez2

  • 1Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens National Medical Center, Washington DC.

Proceedings of Spie--The International Society for Optical Engineering
|June 9, 2017
PubMed
Summary
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This study introduces Marginal Shape Deep Learning (MaShDL) for segmenting deformable objects in medical images. MaShDL improves upon traditional methods by robustly estimating shape parameters, achieving higher accuracy in lung field segmentation.

Area of Science:

  • Medical Imaging
  • Computer Vision
  • Machine Learning

Background:

  • Deep learning (DL) excels at image analysis but struggles with deformable object segmentation.
  • Existing DL methods are limited to pixel classification, not parameter estimation for shape.
  • Classical shape models are prone to local minima and illumination variations.

Purpose of the Study:

  • To develop a novel framework, Marginal Shape Deep Learning (MaShDL), for deformable shape segmentation.
  • To integrate DL's feature learning with statistical shape models for robust parameter estimation.
  • To address the limitations of iterative methods and improve runtime performance.

Main Methods:

  • Proposed MaShDL framework combines DL classifiers with statistical shape models.
Keywords:
chest radiographdeep learninglung fieldshape learningstatistical shape models

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  • Shape parameters are estimated by learning classifiers in marginal eigenspaces.
  • Evaluated on segmenting lung fields in 314 pediatric chest radiographs.
  • Main Results:

    • MaShDL achieved a mean Dice similarity coefficient of 0.927 for lung field segmentation.
    • This significantly outperformed classical Active Shape Models (ASM) which achieved 0.888 (p=0.01).
    • The method demonstrated robustness to local minima and illumination changes.

    Conclusions:

    • MaShDL is the first DL framework for parametric shape learning in deformable object delineation.
    • The framework offers improved accuracy and robustness compared to traditional methods.
    • MaShDL provides an efficient solution for complex multi-parameter estimation problems in medical imaging.