Outbreak of Pseudomonas aeruginosa following endoscopic retrograde cholangiopancreatography

Insights

Five patients developed gentamicin-resistant Pseudomonas aeruginosa infections following endoscopic retrograde cholangiopancreatography. The bacteria were traced to the endoscope, highlighting the critical need for thorough equipment disinfection.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Medical Device Reprocessing

Background:

  • Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure.
  • Hospital-acquired infections are a significant concern in healthcare settings.
  • Pseudomonas aeruginosa is an opportunistic pathogen often associated with healthcare-associated infections.

Purpose of the Study:

  • To report a cluster of gentamicin-resistant Pseudomonas aeruginosa infections.
  • To identify the source of infection in patients undergoing ERCP.
  • To emphasize the importance of endoscope disinfection protocols.

Main Methods:

  • Case series reporting five patients.
  • Infection surveillance during a 12-week period.
  • Microbiological culturing of the endoscope used in patient procedures.

Main Results:

  • Five patients developed gentamicin-resistant Pseudomonas aeruginosa infection post-ERCP.
  • The same endoscope was used for all affected patients.
  • Pseudomonas aeruginosa was successfully cultured from the endoscopic apparatus.

Conclusions:

  • Inadequate disinfection of endoscopes can lead to patient infections.
  • Proper reprocessing of endoscopic equipment is crucial for preventing outbreaks.
  • This case highlights the risk of cross-contamination from shared medical devices.

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