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Published on: June 13, 2025
Outbreak of Pseudomonas aeruginosa following endoscopic retrograde cholangiopancreatography
Abstract:
In a 12 week period five patients developed gentamicin-resistant Pseudomonas aeruginosa infection after endoscopic retrograde cholangiopancreatography with the same endoscope. The organism was subsequently cultured from the endoscopic apparatus. The cases are discussed and the importance of adequate disinfection of endoscopes is re-iterated.
Insights
Five patients developed gentamicin-resistant Pseudomonas aeruginosa infections following endoscopic retrograde cholangiopancreatography. The bacteria were traced to the endoscope, highlighting the critical need for thorough equipment disinfection.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Medical Device Reprocessing
Background:
- Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure.
- Hospital-acquired infections are a significant concern in healthcare settings.
- Pseudomonas aeruginosa is an opportunistic pathogen often associated with healthcare-associated infections.
Purpose of the Study:
- To report a cluster of gentamicin-resistant Pseudomonas aeruginosa infections.
- To identify the source of infection in patients undergoing ERCP.
- To emphasize the importance of endoscope disinfection protocols.
Main Methods:
- Case series reporting five patients.
- Infection surveillance during a 12-week period.
- Microbiological culturing of the endoscope used in patient procedures.
Main Results:
- Five patients developed gentamicin-resistant Pseudomonas aeruginosa infection post-ERCP.
- The same endoscope was used for all affected patients.
- Pseudomonas aeruginosa was successfully cultured from the endoscopic apparatus.
Conclusions:
- Inadequate disinfection of endoscopes can lead to patient infections.
- Proper reprocessing of endoscopic equipment is crucial for preventing outbreaks.
- This case highlights the risk of cross-contamination from shared medical devices.
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