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Area of Science:

  • Obstetrics and Gynecology
  • Pain Management
  • Pharmacology

Background:

  • Post-cesarean delivery pain management often involves opioid prescriptions.
  • Understanding patterns of opioid use and factors influencing consumption is crucial for optimizing patient care and reducing potential misuse.

Purpose of the Study:

  • To characterize postdischarge opioid use in women following cesarean delivery.
  • To examine factors associated with variations in opioid prescribing and consumption.

Main Methods:

  • A prospective observational cohort study included women undergoing cesarean delivery.
  • Weekly follow-up assessed opioid use, pain, and remaining medication.
  • Prescription data were obtained from the state Substance Monitoring Program.

Main Results:

  • 83% of women used opioids post-discharge, with 75% having unused tablets.
  • A significant quantity of unused opioids (2,540 5-mg oxycodone equivalents) were identified.
  • Women who used all prescribed opioids were more likely to report receiving too few tablets.

Conclusions:

  • Most women, particularly those with normal in-hospital opioid use, are prescribed excess opioids post-cesarean delivery.
  • Findings suggest a need to reassess and optimize opioid prescribing quantities to prevent surplus medication.