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Sequence variant at 4q25 near PITX2 associates with appendicitis

Ragnar P Kristjansson1, Stefania Benonisdottir2, Asmundur Oddsson2

  • 1deCODE genetics/Amgen, Inc, Reykjavik, 101, Iceland. ragnarpk@decode.is.

Scientific Reports
|June 10, 2017
PubMed
Summary

A genome-wide study identified a genetic variant near the PITX2 gene associated with an increased risk of appendicitis, particularly in adults. This finding may relate to developmental processes affecting organ symmetry.

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