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Characterizing QT interval prolongation in early clinical development: a case study with methadone

Vincent F S Dubois1, Meindert Danhof1, Oscar Della Pasqua2,3

  • 1Division of Pharmacology Leiden Academic Centre for Drug Research Leiden University Leidenthe Netherlands.

Pharmacology Research & Perspectives
|June 10, 2017
PubMed

Keywords:
Clinical trial simulationsPKPD modelingQT interval prolongationmethadonetranslational pharmacology.

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