Related Experiment Video
Updated: Feb 28, 2026

07:39
Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice
Published on: July 19, 2019
11.8K
[Descemetectomy : An alternative to transplantation?]
E L Bramann1, K Schröder2, S Schrader1
1Universitätsaugenklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Summary
Human corneal transplants are in high demand. A new procedure, Descemet Membrane Extraction (DMx), offers a potential treatment for endothelial diseases like Fuchs dystrophy without needing a transplant.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- Corneal transplantation is the sole cure for endothelial diseases, facing increasing global demand challenges.
- Fuchs endothelial dystrophy necessitates effective treatment options due to transplant shortages.
Observation:
- A clinical case study explored a novel approach for treating endothelial dysfunction.
- The study focused on Descemet's membrane (DMx) removal.
Findings:
- Descemetectomy, a circumscribed removal of Descemet's membrane, was performed.
- This procedure was conducted without subsequent corneal transplantation.
Implications:
- Descemetectomy presents a potential alternative treatment for endothelial corneal diseases.
- This approach may alleviate the strain on global corneal transplant resources.

