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Related Experiment Videos

Exercise training during chronic beta blockade in cardiovascular disease.

G F Fletcher

    The American Journal of Cardiology
    |April 26, 1985
    PubMed
    Summary

    Beta-blocking agents do not hinder exercise training benefits in cardiovascular disease patients. Exercise improves treadmill test duration and reduces resting heart rate, even with cardioselective and nonselective beta-blockers.

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    Area of Science:

    • Cardiology
    • Exercise Physiology

    Background:

    • Cardiovascular disease patients often participate in supervised exercise programs.
    • Beta-blocking agents are commonly prescribed for cardiovascular conditions.

    Purpose of the Study:

    • To investigate if cardioselective and nonselective beta-blocking agents affect exercise training adaptations in cardiovascular disease patients.

    Main Methods:

    • 50 cardiovascular disease patients in an exercise program underwent treadmill tests.
    • Patients were on various beta-blockers (atenolol, propranolol, timolol, metoprolol, nadolol).
    • Tests were conducted initially and at 3-month intervals.

    Main Results:

    • Treadmill test duration significantly increased (p < 0.05) from 7.5 to 9.9 minutes.
    • Resting heart rate significantly decreased (p < 0.05) in 35 subjects (from 67.5 to 60.4 bpm).
    • Improvements were observed despite the use of beta-blocking agents.

    Conclusions:

    • Exercise training elicits significant improvements in exercise capacity and resting heart rate in cardiovascular disease patients.
    • These benefits are achievable even when patients are taking cardioselective and nonselective beta-blocking agents.

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