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[Adverse Drug Reactions in Sichuan Children During 2012-2014.]
Objectives:
To determine the characteristics of adverse drug reactions (ADRs) in children.
Methods:
Reported ADRs in the patients aged from 0-18 years were extracted from the 2012-2014 Sichuan ADR surveillance system.The time trend,category of ADRs [system organ class (SOC)],outcomes,and demographic characteristics of the patients were analyzed.
Results:
The reported paediatric ADRs increased over time;most occurred in males (7 709,56.40%) and preschool children (5 928,43.37%).The majorities involved intravenous drips (8 492,62.13%) and skin and appendages (7 510,55.10%).About 267 (1.95%) cases were deemed as serious ADRs,most (120,44.94%) involving whole body consequences.The majority (13 515,98.87%) of patients recovered.But deaths (5,0.04%) were also reported.
Conclusions:
Pediatric ADRs are associated with young age (less than 5 years old) and intravenous drips.Serious ADRs should be identified for early interventions.
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