Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antimicrobial Proteins01:23

Antimicrobial Proteins

14.8K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
14.8K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.2K
What is the Immune System?01:38

What is the Immune System?

137.6K
Overview
137.6K
Humoral Immune Responses01:36

Humoral Immune Responses

84.7K
Overview
84.7K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

10.5K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
10.5K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

2.2K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From "synthetic" to defined microbial communities for clearer terminology.

Nature communications·2026
Same author

Pseudomonas volatiles shape the root transcriptome and microbiome to promote plant growth under drought.

The New phytologist·2026
Same author

Downy mildew disease-suppressive soils transmit a protective core microbiome to the phyllosphere.

The ISME journal·2026
Same author

Microbiome responses to natural <i>Fusarium</i> infection in field-grown soybean plants.

Plant and soil·2026
Same author

The Extended Plant Immune System.

Molecular plant-microbe interactions : MPMI·2025
Same author

Roots: metabolic architects of beneficial microbiome assembly.

Plant physiology·2025

Related Experiment Video

Updated: Feb 28, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.5K

Iron and Immunity.

Eline H Verbon1, Pauline L Trapet1, Ioannis A Stringlis1

  • 1Plant-Microbe Interactions, Institute of Environmental Biology, Department of Biology, Faculty of Science, Utrecht University, 3508 TB Utrecht, The Netherlands;

Annual Review of Phytopathology
|June 10, 2017
PubMed
Summary
This summary is machine-generated.

Iron homeostasis is vital for plant health, influencing interactions with pathogens and beneficial microbes. Understanding iron

Keywords:
coumarinsinduced systemic resistanceiron homeostasisrhizosphere microbiotasiderophores

More Related Videos

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism
05:36

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Published on: February 23, 2024

999
Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.7K

Related Experiment Videos

Last Updated: Feb 28, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.5K
Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism
05:36

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Published on: February 23, 2024

999
Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.7K

Area of Science:

  • Plant biology and microbiology
  • Nutrient homeostasis
  • Host-pathogen interactions

Background:

  • Iron is essential for cellular processes but toxic in excess, necessitating tight iron homeostasis.
  • Iron metabolism plays a critical role in plant-microbe interactions, affecting disease development.
  • Both plants and microbes actively manage iron availability.

Purpose of the Study:

  • To review the current understanding of iron homeostasis in plant-microbe interactions.
  • To highlight the dual role of iron in plant defense and pathogen virulence.
  • To explore the influence of root microbiota on plant disease through iron modulation.

Main Methods:

  • Literature review of studies on iron homeostasis in plant-pathogen and plant-microbe systems.
  • Analysis of molecular mechanisms underlying iron acquisition and regulation in plants and microbes.
  • Synthesis of findings on the impact of iron on plant immunity and microbial strategies.

Main Results:

  • Plants employ iron-withholding or iron-boosting strategies to modulate pathogen virulence and immune responses.
  • Pathogens secrete siderophores to scavenge iron, overcoming plant defenses and suppressing immunity.
  • Mutualistic root microbiota compete for iron with pathogens or induce systemic resistance via iron-related signaling.

Conclusions:

  • Iron homeostasis is a central theme in plant-microbe interactions, impacting disease susceptibility and resistance.
  • Manipulating iron availability is a key strategy for both hosts and microbes.
  • Further research into iron's role can lead to novel strategies for crop protection and disease management.