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SR proteins: To shuttle or not to shuttle, that is the question

Marie-Louise Hammarskjold1,2, David Rekosh3,2

  • 1Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA mh7g@virginia.edu.

The Journal of Cell Biology
|June 11, 2017
PubMed
Summary

Serine- and arginine-rich proteins (SR proteins) like SRSF2 and SRSF5 shuttle to the cytoplasm with messenger RNA in pluripotent cells. This shuttling does not occur in differentiated cells, revealing a novel aspect of SR protein function.

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