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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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Allergic Reactions02:06

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ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

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Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
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Disturbances in Heart Rhythm01:29

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Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
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Dysrhythmias II: Classification of Tachyarrhythmias01:28

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Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
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Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

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Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
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Related Experiment Video

Updated: Feb 28, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
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Atrial Fibrillation in Anaphylaxis.

Patricia Rojas-Perez-Ezquerra1, Blanca Noguerado-Mellado1, Cristina Morales-Cabeza1

  • 1Allergy Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

The American Journal of Medicine
|June 12, 2017
PubMed
Summary

Anaphylaxis can trigger cardiac arrhythmias like atrial fibrillation. Prompt diagnosis and collaborative treatment protocols between cardiologists and allergists are crucial for managing these severe allergic reactions and preventing complications.

Keywords:
AnaphylaxisAtrial fibrillationBeta-blockersCalcium channel blockers

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Area of Science:

  • Cardiology
  • Allergology
  • Immunology

Background:

  • Anaphylaxis, a severe allergic reaction, is linked to cardiovascular events.
  • While skin and respiratory symptoms are common, cardiac complications are a leading cause of death in anaphylaxis.

Observation:

  • This study reports three cases of atrial fibrillation triggered by anaphylaxis.
  • Identified etiological agents included Anisakis simplex hypersensitivity and food allergy.

Findings:

  • The heart is both a source and target of mediators released during allergic reactions.
  • Anaphylaxis can induce various arrhythmias, posing a dilemma in prioritizing treatment between the allergic reaction and cardiac events.
  • The use of epinephrine in anaphylaxis patients with cardiac conditions remains a controversial topic.

Implications:

  • Establishing clear treatment protocols between cardiologists and allergists is essential for managing cardiac complications during anaphylaxis.
  • Accurate and timely diagnosis of arrhythmias in anaphylaxis is critical to prevent further complications and improve patient outcomes.